SRP0728
MYO3ALPHA, Active
PRECISIO® Kinase, recombinant
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10 μG
$433.00
$433.00
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10 μG
$433.00
About This Item
UNSPSC Code:
12352202
NACRES:
NA.77
$433.00
Usually ships in 2 weeks.
recombinant
expressed in baculovirus infected Sf9 cells
assay
70-95% (SDS-PAGE)
form
frozen liquid
specific activity
3.0-5.0 nmol/min·mg (radiometric)
mol wt
~76 kDa
concentration
0.1 μg/μL
accession no.
NM_017433
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... MYO3A(53904)
Application
Useful for kinase assay and Western blot.
Biochem/physiol Actions
Recombinant human MYO3alpha (1-434) was expressed by Baculovirus in Sf9 insect cells using an N-terminal GST tag. MYO3alpha belongs to the myosin superfamily which are members of the large myosin superfamily and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as MYO3alpha, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors (1). MYO3alpha plays an important role in hearing in humans and mutations in the MYO3alpha have been shown to cause nonsyndromic progressive hearing loss (2). MYO3alpha is highly expreesed in retina and cochlea.
Reconstitution
Formulated in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.
Storage and Stability
Store in aliquots at -70°C. Avoid freeze/thaw cycles.
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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