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SRP0487

Sigma-Aldrich

Bromodomain Non-Acetylated Ligand 2

≥95% (HPLC)

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0.5 ML
$761.00

About This Item

UNSPSC Code:
12352202
NACRES:
NA.32

$761.00


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assay

≥95% (HPLC)

form

aqueous solution

mol wt

2723.2 kDa

packaging

pkg of 5 mL

shipped in

dry ice

storage temp.

−20°C

General description

The Bromodomain Non-acetylated Ligand 2 is peptide histone H3 (1-21). It contains an C-terminal GG linker, followed by a biotinylated Lys. Bromodomains function as acetyl-lysine binding domains, and bromodomain/acetyl-lysine recognition can regulate histone modification, DNA replications, chromatin remodeling, and gene transcription. This peptide is suitable for use as a negative control for several bromodomains including ATAD2 and BAZ2B.

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable


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Pil-Hoon Park et al.
American journal of physiology. Gastrointestinal and liver physiology, 289(6), G1124-G1136 (2005-08-06)
Ethanol treatment increases gene expression in the liver through mechanisms that are not clearly understood. Histone acetylation has been shown to induce transcriptional activation. We have investigated the characteristics and mechanisms of ethanol-induced histone H3 acetylation in rat hepatocytes. Immunocytochemical

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