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SRP0483

Sigma-Aldrich

CREBBP (1081-1197) His tag human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Synonym(s):

CBP, CREB binding protein, KAT3A, RSTS

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

assay

≥90% (SDS-PAGE)

form

aqueous solution

mol wt

14.9 kDa

packaging

pkg of 100 μg

storage condition

avoid repeated freeze/thaw cycles

concentration

1.26 mg/mL

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... CREBBP(1387)

General description

Human bromodomain CREB binding protein (CREBBP), also known as CBP, RSTS and KAT3A (GenBank Accession No. NM_004380) amino acids 1081- 1197 with N-terminal His-tag, MW=14.9 kDa, expressed in an E. coli expression system.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Wei-Chien Huang et al.
Molecular cell, 26(1), 75-87 (2007-04-17)
CBP plays a central role in coordinating and integrating multiple signaling pathways. Competition between NF-kappaB and p53 for CBP is a crucial determinant of whether a cell proliferates or undergoes apoptosis. However, how the CBP-dependent crosstalk between these two transcription
I Panagopoulos et al.
Human molecular genetics, 10(4), 395-404 (2001-02-07)
The CBP gene at 16p13 fuses to MOZ and MLL as a result of the t(8;16)(p11;p13) in acute (myelo)monocytic leukemias (AML M4/M5) and the t(11;16)(q23;p13) in treatment-related AML, respectively. We show here that a novel t(10;16)(q22;p13) in a childhood AML

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