All Photos(2)

Key Documents

COO/COA

SRP0333

ITK active mouse

Name: ITK active mouse
Brand: SIGMA

recombinant, expressed in baculovirus infected Sf9 cells, ≥62% (SDS-PAGE)

Synonym(s):

EMT, IL2 inducible T cell kinase, TCSK, TSK

Sign Into View Organizational & Contract Pricing

All Photos(2)

About This Item

CAS Number:

151662-26-9

UNSPSC Code:

12352200

NACRES:

NA.32

This product is discontinued. Contact Technical Servicefor assistance.

biological source

mouse

recombinant

expressed in baculovirus infected Sf9 cells

assay

≥62% (SDS-PAGE)

form

aqueous solution

mol wt

57 kDa

packaging

pkg of 10 μg

storage condition

avoid repeated freeze/thaw cycles

concentration

1 mg/mL

technique(s)

activity assay: suitable
inhibition assay: suitable

NCBI accession no.

NM_010583

UniProt accession no.

Q03526

shipped in

dry ice

storage temp.

−70°C

Gene Information

mouse ... Itk(16428)

General description

Murine recombinant IL2-inducible T-cell kinase (ITK), also known as Lyk and TSK (GenBank Accession No. NM_010583), amino acids 352-620 (end) with N-terminal GST-tag, MW= 57 kDa, expressed in Sf9 cells via a Baculovirus expression system.

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

4044600623

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Characterization of Itk tyrosine kinase: contribution of noncatalytic domains to enzymatic activity.

J Hawkins et al.

Protein expression and purification, 22(2), 211-219 (2001-07-05)

Itk is a Tec family tyrosine kinase found in T cells that is activated upon ligation of the T cell receptor (TCR/CD3), CD2, or CD28. Itk contains five domains in addition to the catalytic domain: pleckstrin homology, Tec homology which

A novel human tyrosine kinase gene inducible in T cells by interleukin 2.

N Tanaka et al.

FEBS letters, 324(1), 1-5 (1993-06-07)

We have cloned a novel human protein tyrosine kinase gene specific to T cells by the polymerase chain reaction method. This gene encodes a 620 amino-acid polypeptide including a catalytic domain for tyrosine kinase, an SH2 domain and an SH3

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service