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SML2817

Sigma-Aldrich

BAY-1797

≥98% (HPLC)

Synonym(s):

N-(4-(3-Chlorophenoxy)-3-sulfamoylphenyl)-2-phenylacetamide, N-[3-(Aminosulfonyl)-4-(3-chlorophenoxy)phenyl]benzeneacetamide

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5 MG
$97.85
25 MG
$332.00

$97.85

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5 MG
$97.85
25 MG
$332.00

About This Item

Empirical Formula (Hill Notation):
C20H17ClN2O4S
CAS Number:
2055602-83-8
Molecular Weight:
416.88
UNSPSC Code:
51111800
NACRES:
NA.77

$97.85

List Price$103.00Save 5%
Web-Only Promotion

Available to ship onApril 29, 2025Details

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

ClC1=CC=CC(OC2=C(C=C(NC(CC3=CC=CC=C3)=O)C=C2)S(=O)(N)=O)=C1

InChI key

CSJYMAFXYMYNCK-UHFFFAOYSA-N

Biochem/physiol Actions

BAY-1797 orally available, potent and selective P2X4 antagonist that is suitable for in vivo studies in rodents. BAY-1797 exhibits potent anti-inflammatory and anti-nociceptive effects in mouse CFA inflammatory pain model.
potent and selective P2X4 antagonist

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Stefan Werner et al.
Journal of medicinal chemistry, 62(24), 11194-11217 (2019-11-21)
The P2X4 receptor is a ligand-gated ion channel that is expressed on a variety of cell types, especially those involved in inflammatory and immune processes. High-throughput screening led to a new class of P2X4 inhibitors with substantial CYP 3A4 induction

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