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Key Documents

SML2621

Sigma-Aldrich

ZT-12-037-01

≥98% (HPLC)

Synonym(s):

N2-cyclopropyl-N4-(1-isopropylpiperidin-4-yl)-6,7-dimethoxyquinazoline-2,4-diamine

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5 MG
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25 MG
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About This Item

Empirical Formula (Hill Notation):
C21H31N5O2
CAS Number:
Molecular Weight:
385.50
UNSPSC Code:
12352200
NACRES:
NA.77

$108.07

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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

N1(CCC(CC1)Nc2nc(nc4c2cc(c(c4)OC)OC)NC3CC3)C(C)C

InChI

1S/C21H31N5O2/c1-13(2)26-9-7-15(8-10-26)22-20-16-11-18(27-3)19(28-4)12-17(16)24-21(25-20)23-14-5-6-14/h11-15H,5-10H2,1-4H3,(H2,22,23,24,25)

InChI key

AMAQJTHMSLYMFT-UHFFFAOYSA-N

Biochem/physiol Actions

potent and selective ATP-competitive inhibitor of STK19 kinase that blocks oncogenic NRAS-driven melanocyte malignant transformation

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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