Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

SML2190

Sigma-Aldrich

BRD5529

≥98% (HPLC)

Synonym(s):

2-[4′-(Aminocarbonyl)[1,4′-bipiperidin]-1′-yl]-5-[(4-methylbenzoyl)amino]-3-pyridinecarboxylic acid

Sign Into View Organizational & Contract Pricing

Select a Size

5 MG
$92.40
25 MG
$369.60

$92.40

List Price$132.00Save 30%
Web-Only Promotion

Available to ship onApril 30, 2025Details

Request a Bulk Order
All Photos(1)

Select a Size

Change View
5 MG
$92.40
25 MG
$369.60

About This Item

Empirical Formula (Hill Notation):
C25H31N5O4
CAS Number:
1358488-78-4
Molecular Weight:
465.54
UNSPSC Code:
12352200
NACRES:
NA.77

$92.40

List Price$132.00Save 30%
Web-Only Promotion

Available to ship onApril 30, 2025Details

Request a Bulk Order

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

Storage temp.

2-8°C

SMILES string

CC1=CC=C(C(NC2=CC(C(O)=O)=C(N3CCC(N4CCCCC4)(C(N)=O)CC3)N=C2)=O)C=C1

InChI

1S/C25H31N5O4/c1-17-5-7-18(8-6-17)22(31)28-19-15-20(23(32)33)21(27-16-19)29-13-9-25(10-14-29,24(26)34)30-11-3-2-4-12-30/h5-8,15-16H,2-4,9-14H2,1H3,(H2,26,34)(H,28,31)(H,32,33)

Inchi Key

ZXWHESBABUHJBE-UHFFFAOYSA-N

Biochem/physiol Actions

BRD5529 is a cell penetrant inhibitor of CARD9-TRIM62 interaction that binds to wt CARD9, preventing TRIM62 binding and ensuing inflammation. BRD5529 binding to CARD9 results in decrease ubiquitination.
Cell penetrant inhibitor of CARD9-TRIM62 interaction

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000302988
0000302986
0000302986
0000302988
0000297516

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Elizaveta S Leshchiner et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(43), 11392-11397 (2017-10-27)
Advances in human genetics have dramatically expanded our understanding of complex heritable diseases. Genome-wide association studies have identified an allelic series of CARD9 variants associated with increased risk of or protection from inflammatory bowel disease (IBD). The predisposing variant of

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service