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SML2138

Sigma-Aldrich

IR415

≥98% (HPLC)

Synonym(s):

N-(2,4-Difluorophenyl)-N′-[3-(1H-imidazol-1-yl)propyl]-thiourea

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5 MG
$84.83
25 MG
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About This Item

Empirical Formula (Hill Notation):
C13H14F2N4S
CAS Number:
452967-14-5
Molecular Weight:
296.34
MDL number:
MFCD00238878
UNSPSC Code:
12352200
NACRES:
NA.77

$84.83

List Price$89.30Save 5%

In StockDetails

Request a Bulk Order

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

S=C(NC1=C(F)C=C(F)C=C1)NCCCN2C=NC=C2

InChI

1S/C13H14F2N4S/c14-10-2-3-12(11(15)8-10)18-13(20)17-4-1-6-19-7-5-16-9-19/h2-3,5,7-9H,1,4,6H2,(H2,17,18,20)

InChI key

KRSBPLFMLHNMPU-UHFFFAOYSA-N

Biochem/physiol Actions

HBx is a viral suppressor of host defenses consisting of RNAi-based silencing of viral genes. It is important for HBV replication and also functions as an RNAi suppressor protein. HBx is considered as emerging target for anti-viral therapy.
selective inhibitor of Hepatitis B Virus X Protein (HBx)

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Subhanita Ghosh et al.
The Journal of biological chemistry, 292(30), 12577-12588 (2017-06-07)
Persistent or chronic infection with the hepatitis B virus (HBV) represents one of the most common viral diseases in humans. The hepatitis B virus deploys the hepatitis B virus X protein (HBx) as a suppressor of host defenses consisting of

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