SML2110
WOBE437
≥98% (HPLC)
Synonym(s):
(2E,4E)-N-[2-(3,4-Dimethoxyphenyl)ethyl]dodeca-2,4-dienamide
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About This Item
Empirical Formula (Hill Notation):
C22H33NO3
CAS Number:
Molecular Weight:
359.50
UNSPSC Code:
12352200
NACRES:
NA.77
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
CCCCCCC/C=C/C=C/C(NCCC1=CC(OC)=C(OC)C=C1)=O
Biochem/physiol Actions
WOBE437 is a highly potent and selective endocannabinoid transport inhibitor. WOBE437 increases endocannabinoid levels in mice. It exhibits potent anxiolytic, anti-inflammatory, and analgesic effects in mice.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Andrea Chicca et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(25), E5006-E5015 (2017-06-07)
The extracellular effects of the endocannabinoids anandamide and 2-arachidonoyl glycerol are terminated by enzymatic hydrolysis after crossing cellular membranes by facilitated diffusion. The lack of potent and selective inhibitors for endocannabinoid transport has prevented the molecular characterization of this process
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