SML1905
KR7 trifluoroacetate salt
≥98% (HPLC)
Synonym(s):
KPWWPRR-NH2 trifluoroacetate salt, Lys-Pro-Trp-Trp-Pro-Arg-Arg-amide trifluoroacetate salt
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About This Item
Empirical Formula (Hill Notation):
C50H73N17O7 · xC2HF3O2
Molecular Weight:
1024.22 (free base basis)
UNSPSC Code:
12352202
assay
≥98% (HPLC)
form
lyophilized solid
color
white to beige
shipped in
wet ice
storage temp.
−20°C
Biochem/physiol Actions
KR7 is a non-toxic and serum stable heptapeptide that inhibits insulin amyloid fibrillation.
KR7 is a non-toxic and serum stable heptapeptide that inhibits insulin amyloid fibrillation. KR7 primarily targets the fiber elongation step.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Bhisma N Ratha et al.
The Journal of biological chemistry, 291(45), 23545-23556 (2016-09-30)
The aggregation of insulin into amyloid fibers has been a limiting factor in the development of fast acting insulin analogues, creating a demand for excipients that limit aggregation. Despite the potential demand, inhibitors specifically targeting insulin have been few in
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