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SML1783

Sigma-Aldrich

BAY-364

≥98% (HPLC)

Synonym(s):

6-(3-Hydroxypropyl)-2-(1-methyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione, BAY-299N

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About This Item

Empirical Formula (Hill Notation):
C23H19N3O4
CAS Number:
Molecular Weight:
401.41
UNSPSC Code:
12352200
NACRES:
NA.77

assay

≥98% (HPLC)

form

powder

color

white to light brown

solubility

DMSO: 5 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

O=C(C1=C2C(C(CCCO)=CC=C23)=CC=C1)N(C4=CC=C(N(C)C(N5)=O)C5=C4)C3=O

Biochem/physiol Actions

BAY-364 (BAY-299N) is structurally similar to selective BRD1/TAF1 inhibitor BAY-299 and serves as inactive control. BAY-364 is inactive against BRD1 and exhibit moderate activity against TAF1 (3 μM). For full characterization details of the active probe, please visit the BAY-299 probe summary on the Structural Genomics Consortium (SGC) website.

BAY-299, the active probe, is available from Sigma. To learn more about and purchase BAY-299, click here.

To learn about other SGC chemical probes for protein targets, visit sigma.com/sgc

Features and Benefits

BAY-364 is a negative control for BAY-299, an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

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