SML1775
K-756
≥98% (HPLC)
Synonym(s):
3-[[1-(6,7-Dimethoxy-4-quinazolinyl)-4-piperidinyl]methyl]-3,4-dihydro-2(1H)-quinazolinone
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C24H27N5O3
CAS Number:
Molecular Weight:
433.50
UNSPSC Code:
12352200
Recommended Products
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
O=C1NC2=C(C=CC=C2)CN1CC3CCN(C4=C(C=C(OC)C(OC)=C5)C5=NC=N4)CC3
Biochem/physiol Actions
K-756 is an orally available, potent and selective tankyrase inhibitor, which binds to the induced-pocket of tankyrase. K-756 is a selective Wnt/β-catenin pathway inhibitor that stabilizes Axin and reduces active β-catenin. K-756 inhibits the proliferation of APC mutant colorectal cancer COLO 320DM and SW403 cell lines.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service