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SML1758

Sigma-Aldrich

Tetrazanbigen

≥98% (HPLC)

Synonym(s):

5,6,13,14-Tetrahydro-4bH-6,7,12,12b-tetraaza-benzo[b]chrysene, TNBG

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About This Item

Empirical Formula (Hill Notation):
C18H16N4
CAS Number:
2121990-04-1
Molecular Weight:
288.35
UNSPSC Code:
12352202
PubChem Substance ID:
329826056

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 5 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

C12=CC=CC=C1N=C3C(NCC4N3CCC5=C4C=CC=C5)=N2

Biochem/physiol Actions

Tetrazanbigen (TNBG) is a potent and selective antitumor drug that induces lipid accumulation in cancer cells.
Tetrazanbigen (TNBG) is a potent and selective antitumor drug that induces lipid accumulation in cancer cells. Tetrazanbigen induces S phase arrest and apoptosis in hepatocellular carcinoma QGY-7701. Tetrazanbigen potently inhibits growth of QGY-7701 cells xenografts in mice.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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