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SML1725

Sigma-Aldrich

RTC13

≥98% (HPLC)

Synonym(s):

(5Z)-2-Amino-5-[[5-(2-nitrophenyl)-2-furanyl]methylene]-4(5H)-thiazolone, (Z)-2-Amino-5-((5-(2-nitrophenyl)furan-2-yl)methylene)thiazolidin-4-one

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5 MG
$69.65
25 MG
$405.00

About This Item

Empirical Formula (Hill Notation):
C14H9N3O4S
CAS Number:
Molecular Weight:
315.30
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

$69.65

List Price$99.50Save 30%
Web-Only Promotion

Check Cart for Availability

Quality Level

assay

≥98% (HPLC)

form

powder

color

yellow to orange

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C1NC(S/C1=C\C2=CC=C(C3=C([N+]([O-])=O)C=CC=C3)O2)=N

InChI

1S/C14H9N3O4S/c15-14-16-13(18)12(22-14)7-8-5-6-11(21-8)9-3-1-2-4-10(9)17(19)20/h1-7H,(H2,15,16,18)/b12-7+

InChI key

CZZAPCPWFCGOCC-KPKJPENVSA-N

Biochem/physiol Actions

RTC13 is a cell-permeable thiazolidinone derivative that promotes ribosomal read-through activity of premature termination codons (PTCs) and effectively restores full-length protein production from transcripts containing nonsense mutations-generated PTCs, including ataxia-telangiectasia (A-T) mutated in A-T lymphoblastoid cell cultures and dystrophin in mdx Duchenne muscular dystrophy (DMD) mice-derived muscle myotubes.
RTC13 is a cell-permeable thiazolidinone derivative that promotes ribosomal read-through activity of premature termination codons (PTCs) and effectively restores full-length protein production.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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