SML1632

Ceftezole Sodium

≥90% (HPLC)

• Synonym(s): (6R,7R)-8-oxo-7-{[2-(tetrazol-1-yl)acetyl]amino}-3-(1,3,4-thiadiazol-2-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt, Alomen, Celoslin, Falomesin
• Empirical Formula (Hill Notation): C₁₃H₁₁N₈O₄S₃ · Na
• CAS Number: 41136-22-5
• Molecular Weight: 462.46
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825976
• NACRES: NA.77

Properties

• biological source: synthetic
• assay: ≥90% (HPLC)
• form: powder
• solubility: H₂O: soluble 200 mg/L
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: O=C1[C@@H](NC(CN2N=NN=C2)=O)[C@]3([H])N1C(C([O-])=O)=C(CSC4=NN=CS4)CC3.[Na+]
• InChI: 1S/C13H12N8O4S3.Na/c22-7(1-20-4-14-18-19-20)16-8-10(23)21-9(12(24)25)6(2-26-11(8)21)3-27-13-17-15-5-28-13;/h4-5,8,11H,1-3H2,(H,16,22)(H,24,25);/q;+1/p-1/t8-,11-;/m1./s1
• InChI key: UGUMHWUOXWFPFH-JHQAJZDGSA-M

Description

Biochem/physiol Actions

Ceftezole is a first generation cephalosporin with antibacterial activity.

Ceftezole is a first generation cephalosporin with antibacterial activity. Ceftezole binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity causing bacterial cell lysis.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319
• pcodes: P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable