Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

SML1302

Sigma-Aldrich

Nap-FF

≥98% (HPLC)

Synonym(s):

(S)-2-[(S)-2-[2-(Naphthalen-6-yl)acetamido]-3-phenylpropanamido]-3-phenylpropanoic acid, 2-Naa-FF, N-[2-(2-Naphthalenyl)acetyl]-L-phenylalanyl-L-phenylalanine

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C30H28N2O4
CAS Number:
Molecular Weight:
480.55
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=CC=C2)C(O)=O)=O)CC3=CC4=CC=CC=C4C=C3

InChI

1S/C30H28N2O4/c33-28(20-23-15-16-24-13-7-8-14-25(24)17-23)31-26(18-21-9-3-1-4-10-21)29(34)32-27(30(35)36)19-22-11-5-2-6-12-22/h1-17,26-27H,18-20H2,(H,31,33)(H,32,34)(H,35,36)/t26-,27-/m0/s1

InChI key

IYVWBKAVHZILOI-SVBPBHIXSA-N

Biochem/physiol Actions

Nap-FF (2-Naa-FF) is a cell penetrant dipeptide that self-assembly and adopt the β-sheet structures to form prion-like nanofibrils of small molecules (PriSM). PriSM of Nap-FF are selectively cytotoxic to gliomas cancer cells in a presence of stromal cells. PriSM of Nap-FF selectively accumulate in cancer cells, impedes the dynamics of cytoskeletal filaments, and induces apoptosis.
Nap-FF is a cell penetrant dipeptide.

pictograms

Skull and crossbonesEnvironment

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service