SML1262

BRD7552

≥98% (HPLC)

• Synonym(s): Ethyl 4-(((((2R,3R,4S,5R,6S)-4,5-bis((benzo[d][1,3]dioxol-5-ylcarbamoyl)oxy)-2-(hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3-yl)oxy)carbonyl)amino)benzoate
• Empirical Formula (Hill Notation): C₃₃H₃₃N₃O₁₅
• CAS Number: 1137359-47-7
• Molecular Weight: 711.63
• MDL number: MFCD28133407
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825754
• NACRES: NA.77

Properties

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: O=C(NC1=CC(OCO2)=C2C=C1)O[C@H]3[C@H](OC(NC4=CC=C(C(OCC)=O)C=C4)=O)[C@@H](CO)O[C@H](OC)[C@@H]3OC(NC5=CC(OCO6)=C6C=C5)=O
• InChI: 1S/C33H33N3O15/c1-3-43-29(38)17-4-6-18(7-5-17)34-31(39)49-26-25(14-37)48-30(42-2)28(51-33(41)36-20-9-11-22-24(13-20)47-16-45-22)27(26)50-32(40)35-19-8-10-21-23(12-19)46-15-44-21/h4-13,25-28,30,37H,3,14-16H2,1-2H3,(H,34,39)(H,35,40)(H,36,41)/t25-,26-,27+,28-,30+/m1/s1
• InChI key: AAOLIMLEFKWKOY-IXMSMLDRSA-N

Description

Biochem/physiol Actions

BRD7552 is a potent inducer of pancreatic and duodenal homeobox 1 (PDX1) transcription factor that enhanced insulin expression.

BRD7552 is a potent inducer of pancreatic and duodenal homeobox 1 (PDX1) transcription factor that enhanced insulin expression. BRD7552 upregulates PDX1 expression in both primary human islets and ductal cells. It appears that BRD7552 induce PDX1 expression through an epigenetic control.

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable