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SML1152

Sigma-Aldrich

GSK137647A

≥98% (HPLC)

Synonym(s):

4-Methoxy-N-(2,4,6-trimethylphenyl)-benzenesulfonamide, N-Mesityl-4-methoxybenzenesulfonamide

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About This Item

Empirical Formula (Hill Notation):
C16H19NO3S
CAS Number:
349085-82-1
Molecular Weight:
305.39
MDL number:
MFCD02007969
UNSPSC Code:
12352200
PubChem Substance ID:
329825685
NACRES:
NA.77

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

CC1=C(NS(C2=CC=C(OC)C=C2)(=O)=O)C(C)=CC(C)=C1

InChI

1S/C16H19NO3S/c1-11-9-12(2)16(13(3)10-11)17-21(18,19)15-7-5-14(20-4)6-8-15/h5-10,17H,1-4H3

InChI key

FQUAFMNPXPXOJE-UHFFFAOYSA-N

Biochem/physiol Actions

GSK137647A is a selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), which is involved in long-chain fatty acid stimulated GLP-1 secretion and has been implicated in glucose homeostasis, adiposity, and regulation of the anti-inflammatory response. GSK137647A has pEC50 values of 6.3, 6.2, and 6.1 for human, mouse and rat FFA4, and pEC50 values < 4.5 for all three species for FFA1, FFA2, and FFA3.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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