SML1028
MPT0B014
≥98% (HPLC)
Synonym(s):
6-Quinolinyl(3,4,5-trimethoxyphenyl)methanone, B014
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About This Item
Empirical Formula (Hill Notation):
C19H17NO4
CAS Number:
Molecular Weight:
323.34
UNSPSC Code:
12352200
NACRES:
NA.77
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
2-8°C
Biochem/physiol Actions
MPT0B014 inhibits tubulin polymerization and disrupts microtubules in the cytoskeleton.
MPT0B014 inhibits tubulin polymerization and disrupts microtubules in the cytoskeleton. The compound MPT0B014 inhibits proliferation of the lung cancer cells A549, H1299, and H226 with IC50 values of 41, 46 and 42 nM, respectively. MPT0B014 induces cell cycle arrest and apoptosis, inhibits tumor growth in lung cancer xenografts, and potentiates inhibition of tumor growth by erlotinib.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
Storage Class
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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