SML0988

CCCI-01

≥98% (HPLC)

• Synonym(s): 5-Nitro-N-(3-pyridinylmethyl)-2-furancarboxamide
• Empirical Formula (Hill Notation): C₁₁H₉N₃O₄
• CAS Number: 215778-97-5
• Molecular Weight: 247.21
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: [N+](=O)([O-])c1[o]c(cc1)C(=O)NCc2cnccc2
• InChI: 1S/C11H9N3O4/c15-11(9-3-4-10(18-9)14(16)17)13-7-8-2-1-5-12-6-8/h1-6H,7H2,(H,13,15)
• InChI key: OBZHOVWNZIVCCZ-UHFFFAOYSA-N

Description

Biochem/physiol Actions

CCCI-01 iinduces the fomation of multipolar spindles in cancer cells.

CCCI-01 induces the fomation of multipolar spindles in cancer cells containing multiple, or supernumerary centromeres. CCCI-01 leads to centromere declustering, disruption of cell cycle and apoptsis in BT-549 breast cancer cells without affecting bipolar spindles in normal primary human mammary epithelial cells.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable