Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

SML0986

Sigma-Aldrich

Divin

≥98% (HPLC)

Synonym(s):

2-[(2-Hydroxy-1-naphthalenyl)methylene]hydrazide-2-methyl-1H-Benzimidazole-1-propanoic acid, N′-[(E)-(2-Hydroxynaphthalen-1-yl)methylidene]-3-(2-methyl-1H-benzimidazol-1-yl)propanehydrazide)

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C22H20N4O2
CAS Number:
1443321-11-6
Molecular Weight:
372.42
UNSPSC Code:
12352202
NACRES:
NA.77

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

General description

Divin is formed by minicell locus C (minC) and minD gene products. Divin is a nonspecific inhibitor of septation. It has an ability to inhibit cell division at all potential division sites.[1]

Biochem/physiol Actions

Divin (DIVision Inhibitor) is an inhibitor of bacterial division with a novel mechanism of action.
Divin (DIVision Inhibitor) is an inhibitor of bacterial division with a novel mechanism of action. During bacterial division, more than a dozen different proteins assemble at the division site in a specific order to form a complex called the divisome, with the first protein, FtsZ , followed by ‘early′ or ‘late′ proteins based on their temporal localization. Divin blocks cell division by disrupting the spatial and temporal localization of the late division proteins, disrupting their assembly and preventing compartmentalization of the cytoplasm. Divin has been found to be a potent bacteriostatic agent against clinical pathogens with low toxicity against mammalian cells.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
034M4608V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A Division Inhibitor and a Topological Specificity Factor Coded for by the Minicell Locus Determine Proper Placement of the Division Septum in E. coli.
de Boer P A, et al.
Cell, 56(4), 641-649 (1989)

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service