Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

SML0944

Sigma-Aldrich

NK-252

≥98% (HPLC)

Synonym(s):

N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N′-(2-pyridinylmethyl)-urea

Sign Into View Organizational & Contract Pricing

Select a Size

5 MG
$63.30
25 MG
$249.00

$63.30

Available to ship onApril 28, 2025Details

Request a Bulk Order
All Photos(1)

Select a Size

Change View
5 MG
$63.30
25 MG
$249.00

About This Item

Empirical Formula (Hill Notation):
C13H11N5O3
CAS Number:
1414963-82-8
Molecular Weight:
285.26
UNSPSC Code:
12352200
NACRES:
NA.77

$63.30

Available to ship onApril 28, 2025Details

Request a Bulk Order

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

N(Cc3ncccc3)C(=O)Nc1nnc([o]1)c2[o]ccc2

InChI

1S/C13H11N5O3/c19-12(15-8-9-4-1-2-6-14-9)16-13-18-17-11(21-13)10-5-3-7-20-10/h1-7H,8H2,(H2,15,16,18,19)

InChI key

FNSCFQXZZNCDAI-UHFFFAOYSA-N

Biochem/physiol Actions

NK-252 is a very potent, specific activator of the transcription factor Nrf2, which activates antioxidant-associated genes. NK-252 induces expression of an antioxidant response element promoter driven reporter gene, and protects Huh-7 liver cells against H202 induced cytotoxicity.
NK-252 is a very potent, specific activator of the transcription factor Nrf2.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
014M4612V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Discover Bioactive Small Molecules for Gene Regulation

We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service