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SML0892

Sigma-Aldrich

Roslin 2

≥98% (HPLC)

Synonym(s):

1-(Phenylmethyl)-3,5,7-triaza-1-azoniatricyclo[3.3.1.1~3,7~]decane bromide, 1-Benzyl-1,3,5,7-tetraazatricyclo[3.3.1.1~3,7~] decane bromide, 1-Benzyl-3,5,7-triaza-1-azoniaadamantane bromide

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About This Item

Empirical Formula (Hill Notation):
C13H19N4 · Br
CAS Number:
Molecular Weight:
311.22
UNSPSC Code:
12352200
NACRES:
NA.77

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 20 mg/mL, clear

storage temp.

−20°C

Biochem/physiol Actions

Roslin 2 is a p53 reactivator that disrupts the FAK and p53 interaction, and reactivates transcriptional activity of p53 with p21, Mdm-2 and Bax transcriptional targets. Roslin 2 decreases viability and clonogenicity of cancer cells, and inhibits tumor growth.
Roslin 2 is a p53 reactivator that disrupts the FAK and p53 interaction.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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