SML0852

CC4

≥98% (HPLC)

• Synonym(s): (1R,5S)-1,2,3,4,5,6-Hexahydro-3-[2-[(1R,5S)-1,5,6,8-tetrahydro-8-oxo-1,5-methano-2H-pyrido[1,2-a][1,5]diazocin-3(4H)-yl]ethyl]-1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 1,2-BisN-cytisinylethane
• Empirical Formula (Hill Notation): C₂₄H₃₀N₄O₂
• CAS Number: 492-02-4
• Molecular Weight: 406.52
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: H₂O: 5 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• InChI: 1S/C24H30N4O2/c29-23-5-1-3-21-19-9-17(13-27(21)23)11-25(15-19)7-8-26-12-18-10-20(16-26)22-4-2-6-24(30)28(22)14-18/h1-6,17-20H,7-16H2/t17-,18-,19+,20+/m0/s1
• InChI key: LEXDAVFCJPDCNA-VNTMZGSJSA-N

Description

Biochem/physiol Actions

CC4 is a a partial agonist of α4β2 and α6β2 nicotinic acetylcholine receptors with low affinity for α3β4 and α7 containing receptors. CC4 reduces nicotine-induced self-administration and conditioned place preference without affecting motor functions.

CC4 is a a partial agonist of α4β2 and α6β2 nicotinic acetylcholine receptors.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable