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SML0815

Sigma-Aldrich

YMU1

≥98% (HPLC)

Synonym(s):

4-[2-(4,6-Dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl]-1-piperazinecarboxylic acid ethyl ester, Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate

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5 MG
$96.90
25 MG
$491.00

About This Item

Empirical Formula (Hill Notation):
C17H22N4O4S
CAS Number:
Molecular Weight:
378.45
UNSPSC Code:
12352200
NACRES:
NA.77

$96.90


Available to ship onApril 30, 2025Details


Request a Bulk Order

assay

≥98% (HPLC)

form

powder

color

white to light brown

solubility

DMSO: 1 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

[s]1[n]([c](c3c1nc(cc3C)C)=O)CC(=O)N2CCN(CC2)C(=O)OCC

InChI

1S/C17H22N4O4S/c1-4-25-17(24)20-7-5-19(6-8-20)13(22)10-21-16(23)14-11(2)9-12(3)18-15(14)26-21/h9H,4-8,10H2,1-3H3

InChI key

XXUFNNVFZFVKGP-UHFFFAOYSA-N

Biochem/physiol Actions

YMU1 is a cell-permeable and nontoxic inhibitor of hTMPK (thymidylate kinase) that sensitizes tumor cells to doxorubicin in vitro and in vivo.
YMU1 is a cell-permeable and nontoxic inhibitor of hTMPK (thymidylate kinase).

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Articles

Apoptosis regulation involves multiple pathways and molecules for cellular homeostasis.

Cell cycle phases (G1, S, G2, M) regulate cell growth, DNA replication, and division in proliferating cells.

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