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SML0607

Sigma-Aldrich

Ceranib-2

≥98% (HPLC)

Synonym(s):

3-[3-(4-Methoxyphenyl)-1-oxo-2-propen-1-yl]-4-phenyl-2(1H)-quinolinone, 3-[3-(4-Methoxyphenyl)-1-oxo-2-propenyl]-4-phenyl-2(1H)-quinolinone

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5 MG
$82.00
25 MG
$315.00

About This Item

Empirical Formula (Hill Notation):
C25H19NO3
CAS Number:
1402830-75-4
Molecular Weight:
381.42
UNSPSC Code:
12352200
NACRES:
NA.77

$82.00

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Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

shipped in

wet ice

storage temp.

−20°C

Biochem/physiol Actions

Ceranib-2 is a nonlipid ceramidase inhibitor that inhibits cellular ceramidase activity, decreases levels of sphingosine and sphingosine-1-phosphate (S1P), and inhibits cell proliferation.
Ceranib-2 is a nonlipid ceramidase inhibitor.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
0000229418
0000233718
033M4732V

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Violeta Heras et al.
Cell metabolism, 32(6), 951-966 (2020-10-21)
Childhood obesity, especially in girls, is frequently bound to earlier puberty, which is linked to higher disease burden later in life. The mechanisms underlying this association remain elusive. Here we show that brain ceramides participate in the control of female
Gang Pei et al.
The EMBO journal, 40(13), e106272-e106272 (2021-05-05)
Cellular stress has been associated with inflammation, yet precise underlying mechanisms remain elusive. In this study, various unrelated stress inducers were employed to screen for sensors linking altered cellular homeostasis and inflammation. We identified the intracellular pattern recognition receptors NOD1/2

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