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SML0463

Sigma-Aldrich

BPD

≥98% (HPLC)

Synonym(s):

3-(1,3-benzodioxol-5-yl)-4-phenyl-2,5-Furandione

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About This Item

Empirical Formula (Hill Notation):
C17H10O5
CAS Number:
213481-12-0
Molecular Weight:
294.26
MDL number:
MFCD22666591
UNSPSC Code:
12352200
PubChem Substance ID:
329824741

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 15 mg/mL (clear solution)

storage temp.

−20°C

SMILES string

O=C1OC(=O)C(c2ccc3OCOc3c2)=C1c4ccccc4

InChI

1S/C17H10O5/c18-16-14(10-4-2-1-3-5-10)15(17(19)22-16)11-6-7-12-13(8-11)21-9-20-12/h1-8H,9H2

InChI key

IMHGOAWBSJVILI-UHFFFAOYSA-N

Biochem/physiol Actions

BPD inhibits LPS-induced NF-kB signaling by inactivation of TAK-1. BPD is also known to inhibit the expression and activity of COX-2.

Features and Benefits

This compound is featured on the Cytokine Receptors (Interleukin-1 Receptor/TIR Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

hcodes

H302,H400

pcodes

P273

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Graciela Sotelo et al.
BMC evolutionary biology, 20(1), 23-23 (2020-02-11)
The flat periwinkles, Littorina fabalis and L. obtusata, are two sister species widely distributed throughout the Northern Atlantic shores with high potential to inform us about the process of ecological speciation in the intertidal. However, whether gene flow has occurred
Carla Sharp et al.
Assessment, 26(6), 1014-1029 (2018-07-14)
DSM-5 (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition) Section II criteria for borderline personality disorder (BPD) lack developmental operationalization. The aim of the current study was to evaluate whether DSM criteria operate similarly across adolescents and adults to
Ilaria Cataldo et al.
Research in developmental disabilities, 82, 27-38 (2017-10-17)
Oxytocin plays an important role in the modulation of social behavior in both typical and atypical contexts. Also, the quality of early parental care sets the foundation for long-term psychosocial development. Here, we review studies that investigated how oxytocin receptor
Johanna Köhling et al.
Journal of personality disorders, 30(6), 776-795 (2015-12-02)
The quality of depression in borderline personality disorder (BPD) was reported to differ from that in patients with major depressive disorder (MDD) only. However, little is known about affect dynamics in "borderline-depression." The authors assessed affective instability and reactivity in
Niall M McGowan et al.
Translational psychiatry, 9(1), 195-195 (2019-08-23)
Bipolar disorder (BD) and borderline personality disorder (BPD) are two psychiatric disorders with overlapping features that can be challenging to separate diagnostically. Growing evidence suggests that circadian rhythm disturbances are associated with psychiatric illness, however circadian patterns of behaviour have
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