SML0457

AE9C90CB

≥98% (HPLC)

• Synonym(s): N-[(1a,5a,6a)-3-Azabicyclo[3.1.0]hex-6-ylmethyl]-a-hydroxy-N-methyl-a-phenyl-benzeneacetamide hydrochloride (1:1)
• Empirical Formula (Hill Notation): C₂₁H₂₄N₂O₂ · HCl
• CAS Number: 893426-98-7
• Molecular Weight: 372.89
• UNSPSC Code: 12352200
• PubChem Substance ID: 329824736
• NACRES: NA.77

Properties

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: H₂O: 15 mg/mL (clear solution)
• storage temp.: 2-8°C
• SMILES string: Cl.CN(C[C@@H]1[C@H]2CNC[C@@H]12)C(=O)C(O)(c3ccccc3)c4ccccc4
• InChI: 1S/C21H24N2O2.ClH/c1-23(14-19-17-12-22-13-18(17)19)20(24)21(25,15-8-4-2-5-9-15)16-10-6-3-7-11-16;/h2-11,17-19,22,25H,12-14H2,1H3;1H/t17-,18+,19+;
• InChI key: YHBAWCACDJQGDL-MSFHQNQXSA-N

Description

Biochem/physiol Actions

AE9C90CB is a muscarinic acetylcholine receptor antagonist with 20-fold selectivity for M3 receptor subtypes compared to M2. In an in vivo assay, AE9C90CB was approximately 5 times more selective for inhibiting carbachol-induced urinary bladder contraction, compared to saliva production.

AE9C90CB is a tissue specific M3 muscarinic receptor antagonist.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable