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SML0380

Sigma-Aldrich

FMP-API-1

≥98% (HPLC)

Synonym(s):

3,3′-Diamino-4,4′-dihydroxydiphenylmethane, 4,4′-Methylenebis(2-aminophenol), Bis(3-amino-4-hydroxyphenyl)methane

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About This Item

Empirical Formula (Hill Notation):
C13H14N2O2
CAS Number:
16523-28-7
Molecular Weight:
230.26
MDL number:
MFCD00443347
UNSPSC Code:
12352200
PubChem Substance ID:
329825380
NACRES:
NA.77

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: >10 mg/mL

storage temp.

−20°C

SMILES string

Nc1cc(Cc2ccc(O)c(N)c2)ccc1O

InChI

1S/C13H14N2O2/c14-10-6-8(1-3-12(10)16)5-9-2-4-13(17)11(15)7-9/h1-4,6-7,16-17H,5,14-15H2

InChI key

KCFVSHSJPIVGCG-UHFFFAOYSA-N

Biochem/physiol Actions

FMP-API-1 is an inhibitor of AKAP-PKA interactions in vitro and in cultured cardiac myocytes that activates PKA. Apparently, FMP-API-1 binds to a novel allosteric regulatory site.
FMP-API-1 is an inhibitor of AKAP-PKA interactions.

Features and Benefits

This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Other Notes

Air Sensitive

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317,H319

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
062M4612V

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