SML0193

JFD01307SC

≥95% (HPLC)

• Synonym(s): N-(Tetrahydro-1,1-dioxido-3-thienyl)-glycine
• Empirical Formula (Hill Notation): C₆H₁₁NO₄S
• CAS Number: 51070-56-5
• Molecular Weight: 193.22
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825219
• NACRES: NA.77

Properties

• assay: ≥95% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to tan
• solubility: DMSO: ≥5 mg/mL at ~60 °C
• storage temp.: 2-8°C
• SMILES string: OCC(=O)CNC1CCS(=O)(=O)C1
• InChI: 1S/C7H13NO4S/c9-4-7(10)3-8-6-1-2-13(11,12)5-6/h6,8-9H,1-5H2
• InChI key: JQQXDZXXSDLRBC-UHFFFAOYSA-N

Description

Application

JFD01307SC may be used in glutamine synthetase-mediated cell signaling studies.

Biochem/physiol Actions

Glutamine synthetase inhibitor; anti-tuberculosis agent

JFD01307SC is a glutamine synthetase inhibitor and anti-tuberculosis agent. It is believed to act as a mimic of L-Glutamate and thus target enzymes involved in glutamine biosynthesis. JFD01307SC showed activity against M. tuberculosis with MIC in the range of 8 to 16 μg/ml.

Features and Benefits

This compound is featured on the Glutamate/GABA Synthesis and Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class: 13 - Non Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable