SML0182

bPiDl hydrate

≥98% (HPLC)

• Synonym(s): 1,1′-(1,10-decanediyl)bis[3-methyl-pyridinium iodide (1:2) hydrate, N,N-decane-1,10-diyl-bis-3-picolinium diiodide hydrate
• Empirical Formula (Hill Notation): C₂₂H₃₄I₂N₂ · xH₂O
• CAS Number: 525596-64-9
• Molecular Weight: 580.33 (anhydrous basis)
• MDL number: MFCD21608520
• UNSPSC Code: 12352202
• PubChem Substance ID: 329825211
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to tan
• solubility: H₂O: ≥10 mg/mL
• storage temp.: 2-8°C
• SMILES string: O.[I-].[I-].Cc1ccc[n+](CCCCCCCCCC[n+]2cccc(C)c2)c1
• InChI: 1S/C22H34N2.2HI.H2O/c1-21-13-11-17-23(19-21)15-9-7-5-3-4-6-8-10-16-24-18-12-14-22(2)20-24;;;/h11-14,17-20H,3-10,15-16H2,1-2H3;2*1H;1H2/q+2;;;/p-2
• InChI key: ILAREMIWZYIULF-UHFFFAOYSA-L

Description

Application

bPiDl hydrate may be used to study nicotinic receptor-mediated signaling.

Biochem/physiol Actions

bPiDI is an α6β2-specific antagonist that inhibits nicotine-evoked and endogenous dopamine release from rat striatal slices (IC₅₀ = 150 nM, I_max = 55%). bPiDI treatment decreases nicotine self-administration, and nicotine-induced locomotor activity in rats.

bPiDl is a selective α6β2-specific nicotinic receptor antagonist

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable