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SML0180

Aceclidine hydrochloride

≥98% (HPLC)

Synonym(s):

1-Azabicyclo[2.2.2]oct-3-yl acetate hydrochloride, 3-Acetoxyquinuclidine hydrochloride

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10 MG

$87.60

50 MG

$289.00

$87.60

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About This Item

Empirical Formula (Hill Notation):
C9H15NO2 · HCl
CAS Number:
6109-70-2
Molecular Weight:
205.68
PubChem Substance ID:
329825209
UNSPSC Code:
12352200
NACRES:
NA.77
EC Number:
228-071-5
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
100
Storage condition:
desiccated

Key Documents

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Quality Level

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to tan

solubility

H2O: ≥15 mg/mL at ~60 °C

storage temp.

−20°C

SMILES string

Cl.CC(=O)O[C@H]1CN2CC[C@H]1CC2

InChI

1S/C9H15NO2.ClH/c1-7(11)12-9-6-10-4-2-8(9)3-5-10;/h8-9H,2-6H2,1H3;1H/t9-;/m0./s1

InChI key

LWWSARSTZGNKGV-FVGYRXGTSA-N

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SML0350SML2947SML2491
Aceclidine hydrochloride ≥98% (HPLC)

Sigma-Aldrich

SML0180

Aceclidine hydrochloride

AZD-7762 hydrochloride ≥98% (HPLC)

Sigma-Aldrich

SML0350

AZD-7762 hydrochloride

Penehyclidine hydrochloride ≥98% (HPLC)

Sigma-Aldrich

SML2947

Penehyclidine hydrochloride

Azasetron hydrochloride ≥98% (HPLC)

Sigma-Aldrich

SML2491

Azasetron hydrochloride

form

powder

form

powder

form

powder (hygroscopic)

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage condition

desiccated

storage condition

desiccated

storage condition

desiccated

storage condition

desiccated

solubility

H2O: ≥15 mg/mL at ~60 °C

solubility

DMSO: 15 mg/mL, clear

solubility

H2O: 2 mg/mL, clear

solubility

H2O: 2 mg/mL, clear

Application

Aceclidine hydrochloride may be used in muscarinic acetylcholine receptor-mediated cell signaling studies.

Biochem/physiol Actions

Aceclidine hydrochloride is a parasympathomimetic drug with weak anticholinesterase activity. It acts on cholinergic nerve-endings, lowers intraocular pressure and potent therapeutic agent for open-angle glaucoma.[1]
Aceclidine is a non-selective muscarinic acetylcholine receptor partial agonist that is effective in reducing intraocular pressure.
Muscarinic receptor partial agonist
Aceclidine at a concentration of 5 and 50 μg is capable of enhancing the outflow facility, following ciliary muscle disinsertion.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000416633
0000416632
0000416633
0000416632
101M4716V

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Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

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Aceclidine effects on outflow facility after ciliary muscle disinsertion
Hubbard WC, et al.
Ophthalmologica, 210(5), 303-307 (1996)
Double-blind cross-over comparison of aceclidine and pilocarpine in open-angle glaucoma.
J H Romano
The British journal of ophthalmology, 54(8), 510-521 (1970-08-01)

Articles

Muscarinic Acetylcholine Receptors

Muscarinic acetylcholine receptors mediate acetylcholine actions in CNS and non-nervous tissues, crucial for cell signaling.

Global Trade Item Number

SKUGTIN
SML0180-50MG04061832075099
SML0180-10MG04061832075082

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