SML0168

Fluorescent Histamine H3/H4 receptor Antagonist (H3-633-AN) synthetic

• Empirical Formula (Hill Notation): C₄₄H₄₈BF₂N₈O₃S₂
• Molecular Weight: 849.84
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• storage temp.: −20°C
• Quality Level: 200

Description

Biochem/physiol Actions

The SML0168 ligand was shown to antagonize the activity of the histamine agonist, histamine, in two separate recombinant CHO cell lines expressing either the human H2 or H3-receptor and a cyclic-AMP responsive secreted placental alkaline phosphatase (SPAP) reporter gene.

Features and Benefits

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Reconstitution

Dissolve 0.2 mg in 23.5 ul of DMSO to give a 10mM stock solution. Once reconstituted into DMSO the product, must be stored, preferably in smaller aliquots, at -20°C.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable