SML0134
L2-b
≥98% (HPLC)
Synonym(s):
N,N-Dimethyl-N′-(2-pyridinylmethyl)-1,4-benzenediamine
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About This Item
Empirical Formula (Hill Notation):
C14H17N3
CAS Number:
Molecular Weight:
227.30
UNSPSC Code:
12352203
assay
≥98% (HPLC)
form
powder
storage condition
protect from light
color
white to brown
solubility
DMSO: ≥10 mg/mL
shipped in
wet ice
storage temp.
−20°C
Biochem/physiol Actions
L2-b is a bifunctional Aβ-interacting, metal-chelating molecule that modulates ROS production in, and improves survival of neuroblastoma cells incubated in the presence of Aβ along with Copper or Zinc. In cell-free aggregation studies, L2-b inhibits metal-induced Aβ aggregation, and also promotes the dissociation of Ab aggregates in homogenates of human AD brain samples.
L2-b is a modualtor of metal-Aβ aggregation
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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