SMB00446

Peimine

≥98% (HPLC)

• Synonym(s): (3β,5α,6α)-Cevane-3,6,20-triol, Dihydroisoimperialine, Verticine
• Empirical Formula (Hill Notation): C₂₇H₄₅NO₃
• CAS Number: 23496-41-5
• Molecular Weight: 431.65
• MDL number: MFCD02259442
• UNSPSC Code: 12352205
• PubChem Substance ID: 329825019
• NACRES: NA.25

Properties

• assay: ≥98% (HPLC)
• form: powder
• mp: 223 °C
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: 2-8°C
• SMILES string: C[C@H]1CC[C@@]2([H])[C@](O)(C)[C@@]3([H])CC[C@@]4([H])[C@]5([H])C[C@H](O)[C@@]6([H])C[C@@H](O)CC[C@]6(C)[C@@]5([H])C[C@@]4([H])[C@]3([H])CN2C1
• InChI: 1S/C27H45NO3/c1-15-4-7-25-27(3,31)21-6-5-17-18(20(21)14-28(25)13-15)11-22-19(17)12-24(30)23-10-16(29)8-9-26(22,23)2/h15-25,29-31H,4-14H2,1-3H3/t15-,16-,17+,18+,19-,20-,21-,22-,23+,24-,25-,26+,27-/m0/s1
• InChI key: IUKLSMSEHKDIIP-BZMYINFQSA-N

Description

General description

Peimine is an alkaloid of Traditional Chinese Medicine that produces anti-inflammatory properties.

Biochem/physiol Actions

Peimine is a known MAPK inhibitor, as well as an inhibitor of p38, ERK and JNK phosphorylation, and NFκB activation. Peimine shows antitussive, expectorant and anti-inflammatory effects in vivo.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332
• pcodes: P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable