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SCP0222

Sigma-Aldrich

Prodynorphin 228-256 porcine / Dynorphin B 29 Leumorphin

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500 μG
$200.00
1 MG
$285.00

About This Item

Empirical Formula (Hill Notation):
C161H236N42O48
Molecular Weight:
3527.85
UNSPSC Code:
12352200
NACRES:
NA.77

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assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥75%

storage condition

protect from light

storage temp.

−20°C

Amino Acid Sequence

Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr-Arg-Ser-Gln-Glu-Asp-Pro-Asn-Ala-Tyr-Tyr-Glu-Glu-Leu-Phe-Asp-Val

Application

Leumorphin and prodynorphin are endogenous opioid polypeptide hormones used to study opioid signaling and opioid peptide metabolic processing.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Patrice G Guyenet et al.
Clinical and experimental pharmacology & physiology, 29(3), 238-242 (2002-03-22)
1. The present article reviews several aspects of opioid signalling in the rostral ventrolateral medulla (RVLM) and their implications for the neural control of blood pressure. 2. In the RVLM, preproenkephalin (PPE) mRNA is expressed by bulbospinal cells that are
Invertebrate opiate immune and neural signaling.
George B Stefano et al.
Advances in experimental medicine and biology, 521, 126-147 (2003-03-06)
S R Ojeda et al.
Recent progress in hormone research, 55, 197-223 (2000-10-19)
It is becoming increasingly clear that astroglial cells are active participants in the process by which information is generated and disseminated within the central nervous system (CNS). In the hypothalamus, astrocytes regulate the secretory activity of neuroendocrine neurons. They contribute
Brigitte L Kieffer et al.
Progress in neurobiology, 66(5), 285-306 (2002-05-17)
The endogenous opioid system consists of three opioid peptide precursor genes encoding enkephalins (preproenkephalin, Penk), dynorphins (preprodynorphin, Pdyn) and beta-endorphin (betaend), proopiomelanocortin (POMC) and three receptor genes encoding mu-opiod receptor (MOR), delta-opiod receptor (DOR) and kappa-opiod receptor (KOR). In the

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