SCP0195
MOG Protein 35-55, MOG Peptide Fragment human
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C120H179N35O28S1
Molecular Weight:
2591.99
UNSPSC Code:
12352202
NACRES:
NA.32
Recommended Products
assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥75%
storage condition
protect from light
storage temp.
−20°C
Amino Acid Sequence
Met-Glu-Val-Gly-Trp-Tyr-Arg-Pro-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys
General description
Myelin oligodendrocyte glycoprotein (MOG) is widely expressed at the extracellular surface of myelin sheaths and oligodendrocytes in the central nervous system. The MOG gene is mapped to human chromosome 6p22.1.
Application
MOG Protein 35-55 is used as an antigen/immunogen to induce anti-MOG antibodies to induce experimental diseases such as experimental autoimmune encephalomyelitis (EAE) for study.
Biochem/physiol Actions
Myelin oligodendrocyte glycoprotein (MOG) is believed to function as an adhesion protein that support myelination of nerves. MOG is studied to understand the mechanisms of diseases such as adrenoleukodystrophy, vanishing white matter disease, multiple sclerosis (MS) and Rubella-induced mental retardation.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Huifen Huang et al.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 29(5), 535-545 (2020-05-28)
Multiple sclerosis (MS) is an autoimmune disease characterized by a loss of myelin, limb disabilities and dysregulation of gene expression. Unfortunately, there still is no treatment to cure MS. To explore a novel way to treat MS using currently available
Antibodies to myelin oligodendrocyte glycoprotein in idiopathic optic neuritis.
Nakajima H, et al.
BMJ Open, 5(4), e007766-e007766 (2015)
The discoidin domain receptor 1 as a novel susceptibility gene for schizophrenia.
Roig B, et al.
Molecular Psychiatry, 12(9), 833-833 (2007)
Immune modulation by a tolerogenic myelin oligodendrocyte glycoprotein (MOG) 10?60 containing fusion protein in the marmoset experimental autoimmune encephalomyelitis model.
Kap YS, et al.
Clinical and Experimental Immunology, 180(1), 28-39 (2015)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service