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SCP0121

Sigma-Aldrich

[Des-Cys1]-Calcitonin, salmon

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1 MG
$286.00

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1 MG
$286.00

About This Item

Empirical Formula (Hill Notation):
C142H237N43O47S1
Molecular Weight:
3330.73
UNSPSC Code:
12352209
NACRES:
NA.32

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assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥75%

storage condition

protect from light

storage temp.

−20°C

Amino Acid Sequence

Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2

Application

Calcitonin, a 32 amino acid polypeptide, is involved in the regulation of calcium and phosphorous metabolism often antagonistic to parathyroid hormone (PTH). [Des-Cys1]-Calcitonin, salmon (Des-Cys1-sCT) has the N-terminal cysteine residue removed.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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K Uda et al.
Biological & pharmaceutical bulletin, 22(3), 244-252 (1999-04-29)
Various derivatives of human calcitonin have been synthesized and their biological characteristics compared with those of existing calcitonins. The acute effects of these analogues in reducing serum calcium levels and suppressing appetite were assessed in rats. A calcitonin analogue, PO-1
J H Feyen et al.
Biochemical and biophysical research communications, 187(1), 8-13 (1992-08-31)
Structural requirements for binding to the bone calcitonin (CT) receptor and for CT bioactivity both in vitro and in vivo were assessed for a series of N-terminally truncated, N alpha-acetylated, fragments of salmon calcitonin (sCT). Sequential deletion of amino acid

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