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Key Documents

SBR00015

Sigma-Aldrich

AEBSF Ready Made Solution

Synonym(s):

4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C8H10FNO2S · HCl
CAS Number:
Molecular Weight:
239.69
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.85

$82.10


Available to ship onApril 29, 2025Details


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assay

≥97%

Quality Level

form

liquid

storage condition

protect from light

shipped in

dry ice

storage temp.

−20°C

SMILES string

F[S](=O)(=O)c1ccc(cc1)CCN.[Cl-].[H+]

InChI

1S/C8H10FNO2S.ClH/c9-13(11,12)8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H

InChI key

WRDABNWSWOHGMS-UHFFFAOYSA-N

Application

This solution is provided at 100 mM in water. The stock solution may be diluted 1:100 for a 1 mM working concentration. Recommended concentrations for use are 0.1-1.0 mM.

Biochem/physiol Actions

AEBSF is a specific irreversible serine protease inhibitor. It inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. AEBSF is an excellent alternative to available serine protease inhibitors as it offers superior inhibitory activity and much lower toxicological risk.

Other Notes

The stability of AEBSF decreases rapidly at higher temperatures and at a pH greater than 7.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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