SAB5700461

Anti-Phospho-NDRG1-T346 antibody produced in rabbit

• Synonym(s): CAP43, CMT4D, DRG-1, DRG1, GC4, HMSNL, NDR1, NDRG1, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 33; 35; 42
• species reactivity: human, mouse
• concentration: 0.19 mg/ml
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: Q92597
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pThr346)
• Gene Information: human ... NDRG1(10397)

Description

General description

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Immunogen

A synthetic phosphorylated peptide around T346 of human NDRG1 (NP_001128714.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable