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Key Documents

SAB5300029

Sigma-Aldrich

Monoclonal Anti-PTHR1 antibody produced in mouse

clone 4D2, ascites fluid

Synonym(s):

MGC138426, MGC138452, PFE, PTHR, PTHR1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

4D2, monoclonal

mol wt

66 kDa

species reactivity

human

technique(s)

direct ELISA: 1:10,000
immunohistochemistry: 1:200-1:1,000
indirect immunofluorescence: 1:200-1:1,000
western blot: 1:500-1:2,000

isotype

IgG1

NCBI accession no.

NM_000316

UniProt accession no.

Q03431

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... PTH1R(5745)

Immunogen

Purified recombinant fragment of human PTH1R expressed in E.coli.
Mouse monoclonal antibody raised against PTH1R

Physical form

Ascitic fluid containing 0.03% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
PM1010101

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Jifeng Wen et al.
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The study evaluates the protective effect of mangiferin on osteosarcoma cell proliferation and metastasis. Saos-2 and U2OS cells were treated with mangiferin (25, 50, 75 and 100 µM) for 72 h. Mangiferin reduced the cell viability, invasion, and cell adhesion and migration
Shenglong Li et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 114, 108839-108839 (2019-04-13)
Osteosarcoma is an aggressive malignant neoplasm and cancerous bone tumor. Quercetin is a well-known flavonoid abundant in vegetables, fruits, grains, leaves, and red onions. In the present study, we evaluated the effects of quercetin-induced inhibition of parathyroid hormone receptor 1
Ang Deng et al.
Molecular medicine reports, 16(6), 7987-7992 (2017-10-11)
Indian hedgehog protein (Ihh) is evolutionarily conserved and serves important roles in controlling the differentiation of progenitor cells into osteoblasts. Ihh null mutant mice exhibit a failure of osteoblast development in endochondral bone. Although studies have demonstrated that Ihh signaling
Ang Deng et al.
Experimental and therapeutic medicine, 15(1), 789-794 (2018-02-13)
The proliferative rate of chondrocytes affects bone elongation. Chondrocyte hypertrophy is required for endochondral bone formation as chondrocytes secrete factors required for osteoblast differentiation and maturation. Previous studies have demonstrated that the Indian hedgehog (Ihh) signaling pathway is a key

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