Solute carrier family 9 member A3 (SLC9A3) is also known as Na+/H+ exchanger 3 (NHE3) and is expressed in the brush border epithelium. The gene ID of the protein is 24784.
Specificity
Detects ~84 kDa.
Immunogen
AA809 to 831 of rat sequence
Biochem/physiol Actions
Solute carrier family 9 member A3 (SLC9A3) is an exchanger which takes part in the reabsorption of water and sodium chloride in the proximal tubule of kidneys. It exchanges one Na+ (from the lumen) with one H+ (from the cytosol).
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Physical form
PBS, 50% glycerol, and 0.09% sodium azide
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American journal of physiology. Renal physiology, 307(11), F1249-F1262 (2014-10-10)
The proximal tubule Na(+)/H(+) exchanger 3 (NHE3), located in the apical dense microvilli (brush border), plays a major role in the reabsorption of NaCl and water in the renal proximal tubule. In response to a rise in blood pressure NHE3
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