DUX4 (double homeobox 4) has been mapped to human chromosome 4q35.2. DUX4 is an open reading frame of tandem array D4Z4. It consists of two homeobox sequences.
Specificity
This antibody recognizes human DUX4. Does not cross react with DUX4c.
Immunogen
C-terminal 76 amino acids of DUX4 with glutathione-s-transferase (GST) tag
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy.
Clapp J, et al.
American Journal of Human Genetics, 81(2), 264-279 (2017)
Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements.
Beckers M C, et al.
Gene, 264(1), 51-57 (2001)
Questions
Reviews
★★★★★ No rating value
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.