SAB4700192
Monoclonal Anti-CD48 antibody produced in mouse
clone MEM-102, purified immunoglobulin, buffered aqueous solution
Synonym(s):
Anti-BLAST-1
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100 μG
$290.00
$290.00
Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
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100 μG
$290.00
About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
$290.00
Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
Recommended Products
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
MEM-102, monoclonal
form
buffered aqueous solution
species reactivity
nonhuman primates, human
concentration
1 mg/mL
technique(s)
flow cytometry: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
human ... CD48(962)
General description
Cluster of differentiation 48 (CD48) molecule, also known as BLAST1, is encoded by the gene mapped to human chromosome 1q23.3. CD48 is a glycosyl-phosphatidyl-inositol (GPI)-anchored cell-surface protein of immunoglobulin superfamily. The encoded protein is expressed on various hematopoietic cells.
The antibody MEM-102 reacts with CD48 antigen (Blast-1), a 40-47 kDa GPI-anchored membrane protein (immunoglobulin supergene family) widely expressed on hematopoietic cells; it is negative on granulocytes, platelets and erythrocytes.
Immunogen
Raji human Burkitt′s lymphoma cell line
Application
The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 2 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
Biochem/physiol Actions
Cluster of differentiation 48 (CD48) acts as an adhesion and co-stimulatory molecule and stimulates various effects in B and T lymphocytes, natural killer cells, mast cells and eosinophils. CD48 interacts with its ligand CD2 and other molecules and promotes rearrangement of signaling factors in lipid rafts, Lck-kinase activity and tyrosine phosphorylation.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.
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Storage Class
12 - Non Combustible Liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
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Characterization of the Epstein-Barr Virus-Inducible Gene
Encoding the Human Leukocyte Adhesion and
Activation Antigen BLAST-1 (CD48)
Fisher RC and Thorley-Lawson DA
Molecular and Cellular Biology, 11, 1614-1623 (1991)
CD48: A co-stimulatory receptor of immunity.
Elishmereni M and Levi-Schaffer F
The International Journal of Biochemistry & Cell Biology, 43, 25-28 (2011)
The genetic differences between gallbladder and bile duct cancer cell lines.
Saito S
Oncology Reports, 16, 949-956 (2006)
Soichiro Saito et al.
Oncology reports, 16(5), 949-956 (2006-10-04)
Biliary tract cancers carry dismal prognoses. It is commonly understood that chromosomal aberrations in cancer cells have prognostic and therapeutic implications. However, in biliary tract cancers the genetic changes have not yet been sufficiently studied. The aim of this study
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