SAB4503322

Anti-USP44 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Deubiquitinating enzyme 44, USP44, Ubiquitin carboxyl-terminal hydrolase 44, Ubiquitin thioesterase 44, Ubiquitin-specific-processing protease 44
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 81 kDa
• species reactivity: human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:40000; western blot: 1:500-1:1000
• NCBI accession no.: Q9H0E7
• UniProt accession no.: Q9H0E7
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... USP44(84101)

Description

General description

Anti-USP44 Antibody detects endogenous levels of total USP44 protein.

USP44 (ubiquitin-specific protease 44) codes for a 712 amino acid protein. It belongs to the ubiquitin-specific protease (USP) family. USP44 contains a ZnF-UBP (zinc-finger ubiquitin-specific protease) domain and conserved cysteine, histidine and asparagine/aspartic acid residues.It is abundantly expressed in the nucleus. It is mapped to human chromosome 12q22.

Immunogen

The antiserum was produced against synthesized peptide derived from human USP44.

Immunogen Range: 211-260

Biochem/physiol Actions

USP44 (ubiquitin-specific protease 44) plays a major role in the mitotic checkpoint. Absence of USP44 leads to chromosome mis-segregation, aneuploidy and tumorigenesis in vivo.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable