SAB4502884

Anti-ELOVL4 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Elongation of very long chain fatty acids protein 4
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 36 kDa
• species reactivity: mouse, human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:40000; western blot: 1:500-1:1000
• NCBI accession no.: Q9GZR5
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... ELOV4(6785)

Description

General description

Anti-ELOVL4 antibody detects endogenous levels of total ELOVL4 protein.

The ELOVL4 (elongation of very long chain fatty acids protein 4) gene is mapped to human chromosome 6q14.1. The encoded protein localizes to endoplasmic reticulum. ELOVL4 protein consists of five transmembrane domains, a histidine cluster motif and di-lysine motif at the C-terminus.

Immunogen

The antiserum was produced against synthesized peptide derived from human ELOVL4.

Immunogen Range: 41-90

Biochem/physiol Actions

ELOVL4 (elongation of very long chain fatty acids protein 4) plays an important role in the biosynthesis of very long chain fatty acids (both saturated and unsaturated) in the retina, meibomian gland, skin, testis and brain. Mutation in the gene causes autosomal dominant Stargardt3 macular dystrophy. Variation in ELOVL4 results in spastic quadriplegia, ichthyosis and intellectual disability leading to neuro-ichthyotic disorder.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable