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SAB4502193

Sigma-Aldrich

Anti-PIGH antibody produced in rabbit

affinity isolated antibody

Synonym(s):

PIG-H, Phosphatidylinositol N-acetylglucosaminyltransferase subunit H, Phosphatidylinositol-glycan biosynthesis class H protein

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 21 kDa

species reactivity

mouse, human

concentration

~1 mg/mL

technique(s)

ELISA: 1:40000
immunohistochemistry: 1:50-1:100

NCBI accession no.

Q14442

UniProt accession no.

Q14442

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PIGH(5283)

General description

Anti-PIGH Antibody detects endogenous levels of total PIGH protein.
Phosphatidylinositol glycan anchor biosynthesis class H (PIGH) is an endoplasmic reticulum-associated protein. The cDNA consists of 1394 base pairs. The C-terminal and N-terminal domains of protein face the cytoplasm.

Immunogen

The antiserum was produced against synthesized peptide derived from human PIGH.

Immunogen Range: 137-186

Biochem/physiol Actions

Phosphatidylinositol glycan anchor biosynthesis class H (PIGH) has a role in glycosylphosphatidylinositol-anchor biosynthesis.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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PIG-A and PIG-H, which participate in glycosylphosphatidylinositol anchor biosynthesis, form a protein complex in the endoplasmic reticulum.
Watanabe r, et al.
The Journal of Biological Chemistry, 271(43), 26868-26875 (1996)
Chromosomal assignment of genes involved in glycosylphosphatidylinositol anchor biosynthesis: implications for the pathogenesis of paroxysmal nocturnal hemoglobinuria.
Ware R E, et al.
Blood, 83(12), 3753-3757 (1994)
The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG?A, PIG?H, PIG?C and GPI1.
Watanabe r, et al.
The Embo Journal, 17(4), 877-885 (1998)

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