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SAB4501947

Sigma-Aldrich

Anti-MYO1D antibody produced in rabbit

affinity isolated antibody

Synonym(s):

KIAA0727, Myosin-Id

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100 μG
$522.00

$522.00


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100 μG
$522.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

$522.00


Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 116 kDa

species reactivity

human, mouse, rat

concentration

~1 mg/mL

technique(s)

ELISA: 1:40000
immunohistochemistry: 1:50-1:100

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MYO1D(4642)

General description

Anti-MYO1D antibody detects endogenous levels of total MYO1D protein.The MYO1D (myosin ID) gene is mapped to human chromosome 17q11. In rats, MYO1D is predominantly expressed in brain. The encoded protein belongs to the short-tailed class I myosin family.

Immunogen

The antiserum was produced against synthesized peptide derived from human MYO1D.

Immunogen Range: 825-874

Biochem/physiol Actions

Myosin 1 is involved in cell motility, actin polymerization and vesicular transport.Myosin 1D possess ATPases (adenosine triphosphatase) action, which is inhibited by calcium binding to calmodulin. It is associated with membrane recycling pathway. It is known to be overexpressed during oligodendrocyte myelination. This gene serves as an important biomarker for autism disorder. Myosin 1D maintains cellular growth.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Differential localization and dynamics of class I myosins in the enterocyte microvillus
Benesh AE, et al.
Molecular Biology of the Cell, 21(6), 970-978 (2010)
Myosin I: from yeast to human
Kim SV and Flavell RA
Cellular and Molecular Life Sciences, 65(14), 2128-2137 (2008)
Genome-wide association identifies regulatory Loci associated with distinct local histogram emphysema patterns
Castaldi PJ, et al.
American Journal of Respiratory and Critical Care Medicine, 190(4), 399-409 (2014)
Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia
Martins-de-Souza D, et al.
European Archives of Psychiatry and Clinical Neuroscience, 259(3), 151-163 (2009)

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