SAB4501584

Anti-CD18 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): 95 β, CD18, cell surface adhesion glycoproteins LFA- 1/CR3/p150, complement receptor C3 β, integrin β-2
• UNSPSC Code: 12352203

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 84 kDa
• species reactivity: human, rat, mouse
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:1000; immunofluorescence: 1:100-1:500
• NCBI accession no.: P05107
• UniProt accession no.: P05107
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... ITGB2(3689)

Description

General description

Anti-CD18 Antibody detects endogenous levels of total CD18 protein.
CD18/ ITGB2 (integrin subunit β2) is also termed as Mac-1 or complement receptor 3. The ITGB2 gene is mapped to human chromosome 21q22.3. It is mainly expressed in blood. Anti-CD18 Antibody detects endogenous levels of total CD18 protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human CD18/ITGB2.

Immunogen Range: 720-769

Biochem/physiol Actions

CD18/ ITGB2 (integrin subunit β 2) plays an important role in the progression and function of T-cells. Mutations in ITGB2 results in leukocyte adhesion deficiency type 1, which has an established role in T-cell development and function. ITGB2/CD18 is associated with chronic colitis.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable