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Key Documents

SAB4501121

Sigma-Aldrich

Anti-GAS6 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

AXL receptor tyrosine kinase ligand, GAS-6

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 79 kDa

species reactivity

human

concentration

~1 mg/mL

technique(s)

ELISA: 1:40000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GAS6(2621)

General description

Anti-GAS6 Antibody detects endogenous levels of total GAS6 protein. Growth arrest-specific 6 (GAS6) is a vitamin K-dependent protein, that has a molecular weight of 75kDa. It is located on human chromosome 13q34.

Immunogen

The antiserum was produced against synthesized peptide derived from human GAS6.

Immunogen Range: 291-340

Biochem/physiol Actions

The growth arrest-specific 6 (GAS6) plays an important role in systemic inflammation and coagulation. It modulates inflammation, angiogenesis and atherosclerotic plaque formation. GAS6 also controls cell survival, proliferation, migration and adhesion.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Assignment of the human GAS6 gene to chromosome 13q34 by fluorescene in situ hybridization
Saccone S, et al.
Genomics, 30(1), 122-126 (1995)
Plasma growth arrest-specific 6 levels in term and preterm newborns
Eksi A E, et al.
The Journal of Maternal-Fetal & Neonatal Medicine : The Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 31(9), 1151-1155 (2018)
Association study between GAS6 gene polymorphisms and risk of preeclampsia in Chinese population
Ye L, et al.
Eur. J. Obstet. Gyn. Rep. Biol., 211(9), 122-126 (2017)
TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis
van der Meer J H M, et al.
Blood, 123(16), 2460-2469 (2014)
Plasma Level of Growth Arrest-Specific 6 (GAS6) Protein and Genetic Variations in the GAS6 Gene in Patients With Acute Coronary Syndrome
Jiang L, et al.
American Journal of Clinical Pathology, 131(5), 738-743 (2009)

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